The prolonged state of civil war in Syria has caused a large influx of Syrian refugees in Canada. Refugees may face overwhelming stress in migration and resettlement that can contribute to the development of poor health and mental health outcomes. The purpose of this research was to explore Syrian refugee women’s unique perspectives around their mental health and well-being in the resettlement period. In-depth interviews were used to obtain information about women’s experiences with mental health services and the contextual factors that influence their health and well-being in resettlement. The study’s findings will inform culturally safe mental healthcare services and healthy public policy.